If you calorically restrict mice by 40%, then they can have improved testosterone parameters but only if they're obese to start. And it appears to be that same way in humans as well. So, the easy way to think about it is if you're obese or you have metabolic syndrome, caloric restriction will improve your testosterone.

Cannabinoids itself, whether it's THC or CBD, are not going to reduce testosterone by themself. If it's smoked marijuana, then it's very likely to increase your aromatase, which increases your estrogen... So, that is going to decrease testosterone.

The two strongest ones are likely diet and exercise. For hormone health, specifically resistance training is particularly helpful. For diet, caloric restriction can be particularly helpful, especially with the epidemic of metabolic syndrome that is continuing to ongo in this country and in developed countries, in general.

There is a study in young, healthy men, and they calorically restrict them, and their testosterone does decrease. So, if you're young & healthy and you don't have metabolic syndrome, then caloric restriction will likely decrease your testosterone.

Creatine, like creatine monohydrate, can significantly increase the conversion of testosterone to DHT.

There's a lot of sleep supplements that should not be taken daily, and GABA is one of them. Another one of them is trazodone ... In general, if you're taking a sleep supplement, it should not be taken every night.

If you look at the difference between people who stand a lot, sit a lot, and drive a lot, what you see is a progressive decrease in sperm count. Because when people are sitting, there's an increase in temperature. And then when they're sitting on the hot seat of the car or using the heated seats, it actually kills sperm. I think there are good data on that.

Creatine is interesting because it has multiple different effects. It helps with amino acid synthesis ... It does slightly increase total testosterone, and it also increases the conversion of testosterone to dihydrotestosterone.

Prolactin does have a significant acute increase after ejaculation. It does, to some degree, after orgasm as well. But prolactin acts on the pituitary to inhibit the release of the hormones LH and FSH, of which LH can increase testosterone.

I take 400mg of tongkat ali per day. I take it early in the day, because it has a bit of a stimulant effect ... I've been taking it for years ... I've never cycled it ... My blood work tells me that it causes an increase in free testosterone for me and also an increase in luteinizing hormone for me.

If a man begins TRT, then they develop poor sleep because of sleep apnea. It drastically raises the risk that somebody is going to have sleep apnea.

Let's say you have a diet high in plant polyphenols. Many of those inhibit the enzyme that converts testosterone to DHT.

I've actually seen in my blood work that if I don't get out for a 45-minute jog at least once a week, all of my blood profiles suffer in a direction that I don't want them to go. In particular, testosterone and estrogen move in directions that are not conducive to my goals.

If you have deficient vitamin D, and you replace it, then you will optimize your testosterone.

Just to remind people, the SHBG, sex-hormone binding globulin, is attaching to the testosterone molecule and limiting the amount of so-called free testosterone that's available to have its impact on cells.

Testosterone is normally released in a pulsatile manner. So, it's high in the morning and low in the evening. Whereas if you're on testosterone therapy, then you're going to have a steady state. So, your testosterone level is going to be pretty much the same, even in the evening.

Actually, I saw an interesting paper that said that for every two degree increase in temperature of the scrotum, there's a 20%, decrease in spermatogenesis and viability of sperm.

I do avoid drinking out of cans or plastics that may have BPA, or Bisphenol A, in them. Bisphenol A is known to bind to what I would consider the fifth estrogen receptor ... I would consider it a xenoestrogen.