You can't gauge the internal state of a person based on their external appearance. Somebody could be drooling and laughing hysterically and falling backwards in their chair; they might also be having a transcendent experience that is having a positive impact on their life, or a negative one. But the bottom line is that drug policy shouldn't be based on what people do or don't upload to YouTube.

If you take the exact same dose of LSD every year, I would be amazed if it's the same. I would bet against any resemblance between these experiences because you will be different; you will be in a different mood; you will be thinking about different things. You change all the time—much more than the drug.

The only thing you can conclude is that LSD is never 100 micrograms on a blotter. That is the one number that was never found. They have everything in between but never 100. So, I would say, instead of assuming that it's 100 micrograms, I would assume that it's anything but 100 micrograms.

If you are free to do something, you should do it. If you don't live to the extent of your freedom, then you are letting the prohibitionists win. You're letting them win battles they haven't even fought.

It is a medically recognized fact that these associations with PCP and violence are basically a media fabrication—and a racist and classist one at that.

An active dose of 5-MeO-DMT... Usually 15 milligrams is the dose that people cite as being the desired dose. Sometimes people go up to 20, but 15 is kind of the solid dose that will cause most people to have a transcendent experience.

It's clear that, in problem-solving, it can be helpful to do something that forces you to think about the problem differently. And that might be a psychedelic. It might be something else entirely.