#189 – David Sinclair: Extending the Human Lifespan Beyond 100 Years

The average lifespan of a human that looks after themselves but doesn't pay attention is about 80 ... If you do the right things in your life—which is eat healthy food, don't overeat, don't become obese, do a bit of exercise, get good sleep, and don't stress—that gives you, on average, 14 extra years. That gets you to 94. So, getting to 100, if you just focus on what I'm talking about, it's not a big deal.

While many people are interested/obsessed with what they eat, the data that's come out of animal studies, at least, is it's far more important when you eat than what you. There was a fantastic study a few years ago by my friend... He had 10,000 mice on different diets hoping to find the perfect mix of carbs, protein, and fat. And it turns out that the only ones that lived longer were the ones that only ate once a day.

If there was one thing I would recommend to anybody to slow down aging, it would be to skip a meal or two a day.

When I'm stressed... I can see it in my body—heart rate, hormones. It's clear ... So, you got to work on your brain first and foremost. If you are totally freaked out, agitated all the time, you will live shorter. I'm certain of it.

The idea of going to a doctor once a year for an annual checkup and having males get a finger up their butt... That, to me, is a joke. That's medieval medicine, and that's very soon going to be seen as medieval.

Most people forget that diseases that we get when we get old are 80-90% caused by aging. And we've been trying to fix things with Band-Aids after they occur without even generally talking about the root cause of the problem.

If you're not using AI right now in biology, you're getting left behind.

People that cycle over 80 miles a week have a 40% reduction in a variety of diseases, certainly heart disease.