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The blood-brain barrier is key for brain aging. In fact, nearly 50% of all dementias, including Alzheimer's disease, begin with the breakdown of the smallest vessels in the brain. In fact, biomarkers of blood-brain barrier breakdown precede classical biomarkers of Alzheimer's disease, like tau tangles and amyloid-beta 42
aggregates.
Rhonda Patrick
Circulating LPS Causes Blood-Brain Barrier Breakdown, Facilitating Neuroinflammation
Intestinal Permeability: the Bacterial link to Aging, Brain Barrier Dysfunction & Metabolic Disorder
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