Dr. Rhonda Patrick - Why Eating Fish, But Not Omega-3 Supplements, Can Help Prevent Alzheimer's

Foodist with Darya Rose, Ph.D Go to Podcast Page

Dr. Rhonda Patrick - Why Eating Fish, But Not Omega-3 Supplements, Can Help Prevent Alzheimer's

Foodist with Darya Rose, Ph.D Go to Podcast Page

Darya Rose, Rhonda Patrick

40 Clips

Dec 17, 2018

Top Moments

People with one ApoE4 allele have a 2-3x higher risk for Alzheimer's disease. People with two alleles can have up to a 15x higher risk.

0:19

People With an ApoE4 Allele Have an Increased Risk for Alzheimer's Disease

It seems that certain heavy metals are excreted more through either urine or sweat depending on what compound we're talking about. Arsenic and cadmium are excreted in sweat 15x more than in urine. Mercury, on the other hand, is mostly excreted through urine.

0:18

To Avoid Potential Bacterial Contamination, Rhonda Didn't Eat Broccoli Sprouts While Pregnant

Omega-3 fatty acids in salmon protect against potential mercury toxicity.

0:31

While Pregnant, Rhonda Ate Tons of Salmon While Limiting Her Arsenic & Plastic Exposure

DHA in the phospholipid form gets taken up into the developing fetal brain quicker than DHA in the non-phospholipid form.

0:07

While Pregnant, Rhonda Ate Lots of Salmon Roe; It's High in Phospholipid Form DHA

ApoE4 seems to somehow modify how much DHA is getting into the brain such that it's not getting in there very well.

0:09

DHA Is an Omega-3 Fatty Acid Essential for Transporting Glucose Into the Brain

ApoE4 carriers need the phospholipid form of DHA to get DHA into their brains better.

0:07

ApoE4 Disrupts Blood-Brain Barrier Tight Junctions

Low brain glucose is one of the defining characteristics of Alzheimer's disease.

0:04

DHA Is an Omega-3 Fatty Acid Essential for Transporting Glucose Into the Brain

Intros & Ads

Darya Rose Intro

0:11

Darya Introduces Dr. Rhonda Patrick (Part I)

1:08

Darya Previews the Upcoming Episode

0:39

Darya Introduces Dr. Rhonda Patrick (Part II)

0:04

Clips

Rhonda & Darya Have 1-Year-Old Kids

1:17

Women Should Avoid Caffeine When Trying to Get Pregnant

3:33

caffeine coffee

Darya's Husband, Kevin Rose, Used the Sauna as a Form of Birth Control

2:30

sauna children

Darya Did Her Undergrad Thesis on Aging

0:26

25% of People Have At Least One ApoE4 Allele

2:21

ApoE4 Protects Against Malaria But Increases Alzheimer's Disease Risk

0:35

People With an ApoE4 Allele Have Higher Circulating Cholesterol

1:27

Cutting Out Coconut Oil Lowered Rhonda's LDL Cholesterol

0:43

ApoE Is Made in Brain Cells Called Astrocytes

0:40

brain

People With an ApoE4 Allele Have an Increased Risk for Alzheimer's Disease

0:58

Rhonda's Great-Grandmother Had Alzheimer's Disease

2:06

For ApoE4 Carriers, Adequate Sleep Is Essential for Reducing Alzheimer's Disease Risk

2:33

sleep

Rhonda's Paper Explains How DHA Is Transported Into the Brain Differently in ApoE4 Carriers

0:51

DHA Is an Omega-3 Fatty Acid Essential for Transporting Glucose Into the Brain

1:57

glucose brain

Fish Oil Supplementation Doesn't Reduce Alzheimer's Disease Risk in ApoE4 Carriers

0:51

supplements

DHA Can Enter the Brain in the Free Fatty Acid or Phospholipd Form

2:27

brain

ApoE4 Disrupts Blood-Brain Barrier Tight Junctions

0:51

Fish Roe Contains 38-70x More DHA in the Phospholipid Form Than Fish & Fish Oil

1:31

Why Don't Fish Oil Supplements Contain DHA in the Preferred Phospholipid Form?

2:43

supplements

Rhonda's Paper Hypothesizes Phospholipid Form DHA Is Preferable for ApoE4 Carriers

0:47

Rhonda's Been Eating More Salmon Roe Because of Its Astaxanthin Content

1:10

While Pregnant, Rhonda Ate Lots of Salmon Roe; It's High in Phospholipid Form DHA

1:36

DHA Ameliorates Symptoms & Improves Cognitive Function in Alzheimer's Disease Patients

2:01

Vegans & Vegetarians Should Consume Microalgae Because of Its DHA Content

3:26

brain diet

Genetic Testing for ApoE Genotype Can Be Inaccurate

3:53

genes

Aerobic Exercise Reduces Alzheimer's Disease Risk

1:16

exercise

Rhonda Wears an Oura Ring to Track Her Sleep

1:27

sleep sleeping

Both Darya & Rhonda's Husbands Get Tons of REM Sleep But Little Deep Sleep

1:14

sleep

Rhonda's Micronutrient-Rich Diet Contains Lots of Leafy Greens, Eggs, & Salmon

4:49

diet vegetables

Folate Provides Epigenetic Precursors & Is Essential for Thymine Production

1:44

dna

Vitamin K1 & K2 Help Maintain Calcium Homeostasis

1:30

Darya Takes a Seasonal Approach to Eating

1:29

While Pregnant, Rhonda Ate Tons of Salmon While Limiting Her Arsenic & Plastic Exposure

4:19

To Avoid Potential Bacterial Contamination, Rhonda Didn't Eat Broccoli Sprouts While Pregnant

2:43

Connect With Rhonda Online

1:05

Darya Rose Outro

1:00

Dr. Rhonda Patrick - Why Eating Fish, But Not Omega-3 Supplements, Can Help Prevent Alzheimer's

Foodist with Darya Rose, Ph.DGo to Podcast Page

Dr. Rhonda Patrick - Why Eating Fish, But Not Omega-3 Supplements, Can Help Prevent Alzheimer's

Foodist with Darya Rose, Ph.D

Darya Rose Intro

Darya Introduces Dr. Rhonda Patrick (Part I)

Darya Previews the Upcoming Episode

Darya Introduces Dr. Rhonda Patrick (Part II)

Rhonda & Darya Have 1-Year-Old Kids

Women Should Avoid Caffeine When Trying to Get Pregnant

Darya's Husband, Kevin Rose, Used the Sauna as a Form of Birth Control

Darya Did Her Undergrad Thesis on Aging

25% of People Have At Least One ApoE4 Allele

ApoE4 Protects Against Malaria But Increases Alzheimer's Disease Risk

People With an ApoE4 Allele Have Higher Circulating Cholesterol

Cutting Out Coconut Oil Lowered Rhonda's LDL Cholesterol

ApoE Is Made in Brain Cells Called Astrocytes

People With an ApoE4 Allele Have an Increased Risk for Alzheimer's Disease

Rhonda's Great-Grandmother Had Alzheimer's Disease

For ApoE4 Carriers, Adequate Sleep Is Essential for Reducing Alzheimer's Disease Risk

Rhonda's Paper Explains How DHA Is Transported Into the Brain Differently in ApoE4 Carriers

DHA Is an Omega-3 Fatty Acid Essential for Transporting Glucose Into the Brain

Fish Oil Supplementation Doesn't Reduce Alzheimer's Disease Risk in ApoE4 Carriers

DHA Can Enter the Brain in the Free Fatty Acid or Phospholipd Form

ApoE4 Disrupts Blood-Brain Barrier Tight Junctions

Fish Roe Contains 38-70x More DHA in the Phospholipid Form Than Fish & Fish Oil

Why Don't Fish Oil Supplements Contain DHA in the Preferred Phospholipid Form?

Rhonda's Paper Hypothesizes Phospholipid Form DHA Is Preferable for ApoE4 Carriers

Rhonda's Been Eating More Salmon Roe Because of Its Astaxanthin Content

While Pregnant, Rhonda Ate Lots of Salmon Roe; It's High in Phospholipid Form DHA

DHA Ameliorates Symptoms & Improves Cognitive Function in Alzheimer's Disease Patients

Vegans & Vegetarians Should Consume Microalgae Because of Its DHA Content

Genetic Testing for ApoE Genotype Can Be Inaccurate

Aerobic Exercise Reduces Alzheimer's Disease Risk

Rhonda Wears an Oura Ring to Track Her Sleep

Both Darya & Rhonda's Husbands Get Tons of REM Sleep But Little Deep Sleep

Rhonda's Micronutrient-Rich Diet Contains Lots of Leafy Greens, Eggs, & Salmon

Folate Provides Epigenetic Precursors & Is Essential for Thymine Production

Vitamin K1 & K2 Help Maintain Calcium Homeostasis

Darya Takes a Seasonal Approach to Eating

While Pregnant, Rhonda Ate Tons of Salmon While Limiting Her Arsenic & Plastic Exposure

To Avoid Potential Bacterial Contamination, Rhonda Didn't Eat Broccoli Sprouts While Pregnant

Connect With Rhonda Online

Darya Rose Outro

Darya Rose Intro

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Foodist with Darya Rose, Ph.D Go to Podcast Page